Mario is such a popular series, that we usually get every single game that ever came out with our favorite plumbers. Back in the day we did miss a few however. One of them was Mario & Wario which debuted on the Super Famicom which was the Japanese version of the Super Nintendo.
I guess one of the reasons why we never got the game was because it was controlled by the SNES's mouse.
It was a point and click game where you had to control some fairy to guide Mario around levels.
Which is probably as hard as it sounds.