Even though he's now been defeated numerous times, Bowser's appearance in Super Mario 64 on N64 (and DS) is one his most memorable. Mainly because he shows up all the time.
The boss fights are almost always Bowser and they share a similar method. Mainly to spin Bowser around and throw him into a mine.Very easy at first, but the later levels will make you have to aim when you throw him, and the platform will crumble or tilt like crazy.
The final battle was pretty epic, one of Mario's finest moments.