I remember playing Spider-Man and the X-Men in Arcade's Revenge as a kid. It was one of the few SNES games I personally had in my collection. When you got maybe 3 video games a year, you played whatever you got until you lost your marbles. Honestly a game featuring Spider-Man and the X-Men sounds totally awesome, but this was a disappointing superhero adventure.
The game's plot had Spider-Man rescuing the X-Men (or some of them) from a villain named Arcade. Never heard of him before the game, but he's some random nerdy mad scientist or something. I honestly think Carnage or even Electro is a more menacing super-villain.
You could obviously play as members of the X-Men too later on. Mostly the popular ones like Wolverine, Gambit, and Storm. Each character had their own unique stages and powers. Spider-Man's stage was okay, Wolverine's claw range was microscopic, and Storm's stage was nearly impossible for me.
While it had enough superheroes and bad guys from Marvel to make a fan happy, the game-play was mediocre. The powers and difficulty were so unbalanced that it could hardly be enjoyed. Even in the 90's, there were some decent Marvel games, but this wasn't one of them.